I really don't have a soft spot for any chunk of iron.

Although my first interaction with the 6.2 was with a 1982 GMC JIMMY
A local gal had it and she took it to a shop for some minor repairs (Little crap...hoses, belts yada yada yada) The mechanic told her she needed to get rid of it soon as these things BLOW UP

I traded her a Dodge Ram Charger for it....

The little Red engine ran to 300K miles for me....NEVER BLEW UP EITHER...

Only issue was the 700R4 tranny scattered all over the street one day going to work......

Swapped in a TH350...called it good.....

I don't think any oddities would be noticed when machining a Red block....

The slight difference in the material is not likely to even be noticed.....A well seasoned machinist MIGHT hear a slight difference in the sound of the cutter on a boring bar when boring cylinders.....MAYBE.....