My feeling on the Hi POP units is that unless you are starting life off with a specially set up high output pump thats set on kill I would stick with the standard pressure injectors.

Hi pop will give a slightly better/finer spray mist rersulting in a better burn "maybe"

I also wonder what this is going to do over time to the IP when working things harder to produce the higher pressures.

I stuck a set of squirts in a 6.2 that I had purchased from a shop that I had not dealt with before and they had set them to 6.5 pressures.
The little diesel rat rattled really good.
On a cold morning it sounded like an unhappy powerstroke.
OH YEAH Buddy.
Never had any issues with it though