The Optimizers were designed to retrofit back for every 6.5L engine application with little or no modifications. However, that was for military applications - which typically used the center mount turbo.

My understanding is that the angle of the intake manifold bolts is different. The naturally aspirated or side-mount turbo applications have bolts that are at 90 degrees to the intake manifold surface. Intake bolts that are at 60 degrees to the intake manifold mounting face are found on the center-mount turbo manifold.

I haven’t looked into what would need to be done to change things to accept the NA or side mount turbo intake manifold.