I would not recommend using any diesel fuel treatment that doesn't meet current industry standards for ULSD diesel fuel treatments. A truck's Diesel Oxidation Converter (DOC) and Diesel Particulate Filter (DPF) could be harmed by non-approved diesel fuel treatments. Warranties could also be in jeopardy.

Otherwise, yes, 2-stroke oil does provide some benefits for older diesels, but it is or can be more expensive than when using a commercially available and approved diesel fuel treatment - that typically employs chemistry to improve diesel fuel lubricity.